Kurt Kroenke, MD, MACP

Professor of Medicine, Indiana University School of Medicine
Research Scientist, Indiana University Center for Health Services and Outcomes Research
Research Scientist, William M. Tierney Center for Health Services Research, Regenstrief Institute, Inc.
Director of Education and Training Programs, Regenstrief Institute, Inc.
Core Investigator, VA HSR&D Center for Health Information and Communication

   Dr. Kroenke is Professor of Medicine in the Indiana University School of Medicine and Director of the Career Development, Education and Research Training (CERT) program for the Indiana Clinical and Translational Sciences Institute (CTSI). As part of CERT, he directs the Master of Sciences in Clinical Research and the KL2 Young Investigator programs. As a senior research scientist, he pursues his principal research interests in physical and psychological symptoms, including pain, depression, anxiety and somatization across several platforms, including the VA HSR&D Center for Health Information and Communication, and Regenstrief Institute's William M. Tierney Center for Health Services Research


   Dr. Kroenke is a past as well as current recipient of both NIH and VA HSR&D investigator-initiated grants funding randomized trials to improve the care of patients with pain, depression, and anxiety conditions.  He has developed multiple patient-reported outcome measures which have been translated into 80 or more languages and used globally, including PHQ-9 depression scale, GAD-7 anxiety scale, PHQ-15 somatization scale, PEG pain scale, and P4 suicidality screener. The PHQ-9 and GAD-7 are now used by CMS, VA, FDA, national guidelines, in electronic health records, and scores of research and clinical practice settings.


   Dr. Kroenke is appointed to the Psychological Health Subcommittee, Health Board, at the U. S. Department of Defense and the Science Advisory Committee to the Canadian Minister of Veterans Affairs. He serves on editorial boards for JAMA–Internal Medicine, General Hospital Psychiatry, Psychosomotic Medicine, and Psychosomatics., In 2012, Dr. Kroenke was named Distinguished Educator by the Association of Clinical Research Training (ACRT). He has mentored over thirty-five fellows and junior faculty and has more than 300 peer-reviewed research publications.

Active Projects

I. NIH  (2013-2018)

Indiana CTSI Education/Training/Career Medicine Component (PI)


II. PCORI (2015-2017)

"Incorporating PROMIS Symptom Measures into Primary Care Practice" (PI) 


III. NIH (2012-2017)

"COllaboration to Preserve PEformance in Late Stage Cancer (COPE)" (PI)


IV. VA HSR&D IIR (2013-2017)

"Comprehensive vs. Assisted Management of Mood and Pain Symptoms (CAMMPS) Trial" (PI)


Selected Publications                               |                              Go To PubMed List >>


1. Peng X, Robinson RL, Mease P, Kroenke K, Williams DA, Chen Y, Faries D, Wohlreich M, McCarberg B, Hann D. Long-term evaluation of opioid treatment in fibromyalgia. The Clinical Journal of Pain. 2015 Jan;31(1):7-13.

2. Kroenke K. Telemedicine screening for eye disease. JAMA. 2015 Apr 28;313(16):1666-7.

3. Hirsh AT, Hollingshead NA, Ashburn-Nardo L, Kroenke K. The interaction of patient race, provider bias, and clinical ambiguity on pain management decisions. The Journal of Pain. 2015 Mar 27. pii: S1526-5900(15)00596-9.

4. Outcalt SD, Kroenke K, Krebs EE, Chumbler NR, Wu J, Yu Z, Bair MJ. Chronic pain and comorbid mental health conditions: independent associations of posttraumatic stress disorder and depression with pain, disability, and quality of life. Journal of Behavioral Medicine. 2015 Jun;38(3):535-43.

5. Bair MJ, Ang D, Wu J, Outcalt SD, Sargent C, Kempf C, Froman A, Schmid AA, Damush TM, Yu Z, Davis LW, Kroenke K.  Evaluation of Stepped Care for Chronic Pain (ESCAPE) in Veterans of the Iraq and Afghanistan Conflicts: A Randomized Clinical Trial.  JAMA Internal Medicine. 2015 May 1;175(5):682-9.

6. Hyphantis T, Kotsis K, Kroenke K, Paika V, Constantopoulos S, Drosos AA, Carvalho AF, Guthrie E; ARISTEIA-ABREVIATE Study Group members. Lower PHQ-9 cutpoint accurately diagnosed depression in people with long-term conditions attending the Accident and Emergency Department. Journal of Affective Disorders. 2015 May 1;176:155-63.

7. Kroenke K. A practical and evidence-based approach to common symptoms: a narrative review. Annals of Internal Medicine. 2014 Oct 21;161(8):579-86.

8. Kroenke K. Distance therapy to improve symptoms and quality of life: complementing office-based care with telehealth. Psychosomatic Medicine. 2014 Oct;76(8):578-80.

9. Hyphantis T, Kroenke K, Papatheodorou E, Paika V, Theocharopoulos N, Ninou A, Tomenson B, Carvalho AF, Guthrie E; ARISTEIA-ABREVIATE Study Group members. Validity of the Greek version of the PHQ 15-item Somatic Symptom Severity Scale in patients with chronic medical conditions and correlations with emergency department use and illness perceptions. Comprehensive Psychiatry. 2014 Nov;55(8):1950-9.

10. Kroenke K, Yu Z, Wu J, Kean J, Monahan PO.  Operating characteristics of PROMIS four-item depression and anxiety scales in primary care patients with chronic pain. Pain Medicine. 2014 Nov;15(11):1892-901.

11. Johns SA, Brown LF, Beck-Coon K, Monahan PO, Tong Y, Kroenke K. Randomized controlled pilot study of mindfulness-based stress reduction for persistently fatigued cancer survivors. Psycho-oncology. 2014 Aug 17. [Epub]

12. Choi Yoo SJ, Nyman JA, Cheville AL, Kroenke K. Cost effectiveness of telecare management for pain and depression in patients with cancer: results from a randomized trial.  General Hospital Psychiatry. 2014 Nov-Dec;36(6):599-606.

13. Kroenke K, Krebs EE, Wu J, Yu Z, Chumbler NR, Bair MJ.  Telecare collaborative management of chronic pain in primary care: a randomized clinical trial.  JAMA. 2014 Jul 16;312(3):240-8.

14. Are the harms of false-positive screening test results minimal or meaningful? Kroenke K. JAMA Internal Medicine. 2014 Jun;174(6):961-3.

15. Olfson M, Kroenke K, Wang S, Blanco C. Trends in office-based mental health care provided by psychiatrists and primary care physicians. Journal of Clinical Psychiatry. 2014 Mar;75(3):247-53.

16. Hirsh AT, Hollingshead NA, Matthias MS, Bair MJ, Kroenke K.  The influence of patient sex, provider sex, and sexist attitudes on pain treatment decisions.  Journal of Pain. 2014 May;15(5):551-9.

17. Saliba D, DiFilippo S, Edelen MO, Kroenke K, Buchanan J, Streim J.  Testing the PHQ-9 interview and observational versions (PHQ-9 OV) for MDS 3.0. Journal of the America Medical Directors Association. 2012 Sep;13(7):618-25.

18. Abedin Z, Biskup E, Silet K, Garbutt JM, Kroenke K, Feldman MD, McGee R Jr, Fleming M, Pincus HA. Deriving competencies for mentors of clinical and translational scholars. Clinical Translational Science. 2012 Jun;5(3):273-80.


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