Linda S. Williams, MD

Professor of Neurology, Indiana University School of Medicine
Research Scientist, Indiana University Center for Health Services and Outcomes Research
Research Scientist, William M. Tierney Center for Health Services Research, Regenstrief Institute, Inc.
Core Investigator, VA HSR&D Center for Health Information and Communication
Staff Physician, Richard L. Roudebush VA Medical Center
Co-Principal Investigator, VA HSR&D Precision Monitoring to Transform Care Quality Enhancement Research Initiative (PRIS-M QUERI)

     Dr. Williams is Professor of Neurology in the Indiana University School of Medicine and a Staff Physician in the Richard L. Roudebush VA Medical Center, where she served as Chief of Neurology from 2005 to 2009. As a neurology health services researcher in the IU Center for Health Services and Outcomes Research and Regenstrief Institute's William M. Tierney Center for Health Services Research, she is working to implement evidence to improve stroke care and outcomes. Her primary research interests are developing quality of life measurement methods, evaluating the relationship between post-stroke depression and quality of life, and in using quality of life assessment at the point of care to improve stroke outcomes and process of care.


     Dr. Williams is the co-PI of the VA Precision Monitoring to Transform Care Quality Enhancement Research Initiative (PRIS-M QUERI) – a VA research program whose mission is implement and evaluate electronic clinical quality measures and decision support tools at point of care. The PRIS-M QUERI addresses important implementation questions about how best to use data to activate providers, healthcare teams, and Veterans to improve healthcare delivery and outcomes. Dr. Williams is committed both as a researcher and as a clinician to improving the quality of care for veterans with stroke, and to advancing the science of implementation by testing implementation intervention strategies in real world settings. She has served on guidelines development committees for the American Heart Association (AHA) and American Academy of Neurology (AAN) and on the AHA Cerebrovascular Quality of Care and Outcomes Group.

Dr. Williams is board certified in neurology with special expertise in the areas of brain ischemia, cerebrovascular disorders, cognition disorders, dementia-related behavioral disorders, epilepsy, seizure disorders, and stroke. She is a staff physician at Richard L. Roudebush VA Medical Center.


  Cerebrovascular disease; Research outcomes



Hospital Privileges:  
     Richard L. Roudebush VA Medical Center  



School of Medicine      Indiana University School of Medicine
Residency      University of Rochester
Fellowship      Indiana University School of Medicine

Active Projects

I. VA QUERI  (2013-2017)

"Stroke VA Quality Enhancement Research Initiative (QUERI)" (PI)     

The program accomplishes its mission by engaging a network of local and national collaborators to secure VA HSR&D and other competitive grants to develop, implement, and evaluate interventions to improve VA stroke care nationwide.


II. VA QUERI RRP  (2014-2015)

"e-Measurement of Meaningful Use Stroke Electronic Quality Indicators (MUSE-QI)" (PI)


III. VA HSR&D                                                            02/15/2010 - 02/14/2013        

"Intervention for Stroke Performance Improvement using Redesign Engineering" (PI)

Study designed to determine clinical and administration response to the report from the Office of Quality Improvement on stroke performance indicators and conduct a formative evaluation in order to design and execute an intervention in year 3 to improve stroke care performance.

Selected Publications                               |                             Go To PubMed List >>

1. Chung ML, Bakas T, Plue LD, Williams LS. Effects of Self-esteem, Optimism, and Perceived Control on Depressive Symptoms in Stroke Survivor-Spouse Dyads. Journal of Cardiovascular Nursing. 2015 Feb 5. [Epub ahead of print]

2. Daggett VS, Woodward-Hagg H, Damush TM, Plue L, Russell S, Allen G, Williams LS, Chumbler NR, Bravata DM. Health Care Systems Redesign Project to Improve Dysphagia Screening. Journal of Nursing Care Quality. 2015 Jul-Sep;30(3):226-32.

3. Keyhani S, Myers LJ, Cheng E, Hebert P, Williams LS, Bravata DM. Effect of clinical and social risk factors on hospital profiling for stroke readmission: a cohort study. Annals of Internal Medicine. 2014 Dec 2;161(11):775-84.

4. Damush TM, Miller KK, Plue L, Schmid AA, Myers L, Graham G, Williams LS. National implementation of acute stroke care centers in the Veterans Health Administration (VHA): formative evaluation of the field response. Journal of General Internal Medicine. 2014 Dec;29 Suppl 4:845-52.

5. Vickrey BG, Williams LS.Posttraumatic stress disorder after cerebrovascular events: broadening the landscape of psychological assessment in stroke and transient ischemic attack. Stroke. 2014 Nov;45(11):3182-3.

6. Smith EE, Saver JL, Alexander DN, Furie KL, Hopkins LN, Katzan IL, Mackey JS, Miller EL, Schwamm LH, Williams LS; AHA/ASA Stroke Performance Oversight Committee. Clinical performance measures for adults hospitalized with acute ischemic stroke: performance measures for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014 Nov;45(11):3472-98.

7. Lich KH, Tian Y, Beadles CA, Williams LS, Bravata DM, Cheng EM, Bosworth HB, Homer JB, Matchar DB. Strategic planning to reduce the burden of stroke among veterans: using simulation modeling to inform decision making. Stroke. 2014 Jul;45(7):2078-84.

8. Bettger JP, Zhao X, Bushnell C, Zimmer L, Pan W, Williams LS, Peterson ED. The association between socioeconomic status and disability after stroke: findings from the Adherence eValuation After Ischemic stroke Longitudinal (AVAIL) registry.  BMC Public Health. 2014 Mar 26;14:281.

9. Phipps MS, Jia H, Chumbler NR, Li X, Castro JG, Myers J, Williams LS, Bravata DM. Rural-urban differences in inpatient quality of care in US Veterans with ischemic stroke. Journal of Rural Health. 2014 Winter;30(1):1-6.

10. Yu Z, Liu L, Bravata DM, Williams LS.Joint model of recurrent events and a terminal event with time-varying coefficients. Biometrics Journal. 2014 Mar;56(2):183-97.

11. Chumbler NR, Jia H, Phipps MS, Li X, Ordin D, Williams LS, Myers LJ, Bravata DM. Postdischarge quality of care: do age disparities exist among Department of Veterans Affairs ischemic stroke patients? Journal of Rehabilitation Research and Development. 2013;50(2):263-72.

12. Schmid AA, Yaggi HK, Burrus N, McClain V, Austin C, Ferguson J, Fragoso C, Sico JJ, Miech EJ, Matthias MS, Williams LS, Bravata DM. Circumstances and consequences of falls among people with chronic stroke. Journal of Rehabilitation Research and Development. 2013;50(9):1277-86.

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