Matthew J. Bair, MD, MS

Associate Professor of Medicine, Indiana University School of Medicine
Research Scientist, Indiana University Center for Health Services and Outcomes Research
Research Scientist, William M. Tierney Center for Health Services Research, Regenstrief Institute, Inc.
Core Investigator, VA HSR&D Center for Health Information and Communication

   Dr. Bair is a core investigator for the VA Health Services Research and Development Center for Health Information and Communication, an attending physician in the Inpatient Medicine Service at Richard L. Roudebush VA Medical Center, and Associate Professor of Medicine in the Indiana University School of Medicine. His specific program of research is focused on affective disorders (e.g. depression and anxiety) and chronic pain and developing strategies to improve pain management in the primary care setting.  


   Dr. Bair currently serves as editorial board member for the journals Pain Medicine and Pain Practice and deputy editor for the Journal of General Internal Medicine.  He is director of the Health Services Research & Development Advanced Fellowship Program at Roudebush VA Medical Center, and teaches implementation research methods and evidence-based medicine to medical residents, fellows, and IUPUI junior faculty.  In 2013, IU medical students selected him as “Outstanding Educator”, and in 2014, he received an Indiana University Teaching Award for his instruction in the Student Outpatient Clinic.


   In 2007, Dr. Bair was awarded a Merit Review grant from the VA Rehabilitative Research & Development to conduct a randomized controlled trial to compare a combination of pain treatments, including algorithm-based analgesics, pain self-management, and cognitive behavioral therapy, versus usual care. This was the first of many interventions for chronic pain treatment of Operation Enduring Freedom and Operation Iraqi Freedom veterans.

Dr. Bair is board certified in Internal Medicine and a staff physician in Richard L. Roudebush VA Medical Center. Clinical interests include effective pain management in primary care settings.



  Internal Medicine



Hospital Privileges:  
     Richard L. Roudebush VA Medical Center  



School of Medicine      Medical College of Wisconsin

     Fitzsimons Army Medical Center

       University of Colorado Health Sciences
Fellowship      Regenstrief Institute, Inc. / Indiana University
Fellowship      Richard L. Roudebush VA Medical Center / Indiana University

Active Studies

I. VA RR&D (2013-2017)

"Pain Outcomes Comparing Yoga Versus Structured Exercise (POYSE) Trial" (PI)

This is a randomized clinical trial to compare the effectiveness of a yoga-based intervention (YOGA) with that of a structured exercise program (SEP) for subjects with fibromyalgia.

II. VA OAA (2013-2015)

PhD Postdoctoral Training in Health Services Research and Postdoctoral Training in Medical Informatics  (Role: Director)


III. VA HSR&D IIR (2011-2015)

"Care Management for the Effective Use of Opioids (CAMEO)" (PI)

This is a randomized clinical trial to compare the effectiveness of pharmacological vs. behavioral approaches for chronic lower back pain.

Selected Publications                               |                            Go To PubMed List >>

1. Bair MJ, Bohnert AS. Overdoses in Patients on Opioids: Risks Associated with Mental Health Conditions and Their Treatment. Journal of General Internal Medicine. 2015 Apr 21. [Epub ahead of print]

2. Outcalt SD, Kroenke K, Krebs EE, Chumbler NR, Wu J, Yu Z, Bair MJ. Chronic pain and comorbid mental health conditions: independent associations of posttraumatic stress disorder and depression with pain, disability, and quality of life. Journal of Behavioral Medicine. 2015 Jun;38(3):535-43.

3. Bair MJ, Ang D, Wu J, Outcalt SD, Sargent C, Kempf C, Froman A, Schmid AA, Damush TM, Yu Z, Davis LW, Kroenke K.  Evaluation of Stepped Care for Chronic Pain (ESCAPE) in Veterans of the Iraq and Afghanistan Conflicts: A Randomized Clinical Trial.  JAMA Internal Medicine. 2015 May 1;175(5):682-9.

4. Merlin JS, Walcott M, Kerns R, Bair MJ, Burgio KL, Turan JM.  Pain Self-Management in HIV-Infected Individuals with Chronic Pain: A Qualitative Study.  Pain Medicine. 2015 Apr;16(4):706-14.

5. Denneson LM, Teo AR, Ganzini L, Helmer DA, Bair MJ, Dobscha SK. Military Veterans' Experiences with Suicidal Ideation: Implications for Intervention and Prevention. Suicide and Life Threatening Behaviors. 2014 Nov 3.  [Epub ahead of print]

6. Matthias MS, McGuire AB, Kukla M, Daggy J, Myers LJ, Bair MJ. A brief peer support intervention for veterans with chronic musculoskeletal pain: a pilot study of feasibility and effectiveness. Pain Medicine. 2015 Jan;16(1):81-7.

7. Outcalt SD, Ang DC, Wu J, Sargent C, Yu Z, Bair MJ. Pain experience of Iraq and Afghanistan Veterans with comorbid chronic pain and posttraumatic stress. Journal of Rehabilitation Research & Development. 014;51(4):559-70.

8. Hollingshead NA, Matthias MS, Bair MJ, Hirsh AT.  Impact of race and sex on pain management by medical trainees: a mixed methods pilot study of decision making and awareness of influence.  Pain Medicine. 2015 Feb;16(2):280-90.

9. Kroenke K, Krebs EE, Wu J, Yu Z, Chumbler NR, Bair MJ.  Telecare collaborative management of chronic pain in primary care: a randomized clinical trial. JAMA. 2014 Jul 16;312(3):240-8.

10. Bair MJ. Patient encounters of a difficult kind. Journal of General Internal Medicine. 2014 Aug;29(8):1083-4.

11. Denneson LM, Corson K, Helmer DA, Bair MJ, Dobscha SK, Mental health utilization of new-to-care Iraq and Afghanistan Veterans following suicidal ideation assessment.  Psychiatry Research. 2014 Jul 30;217(3):147-53.

12. Yano EM, Bair MJ, Carrasquillo O, Krein SL, Rubenstein LV.  Patient Aligned Care Teams (PACT): VA's journey to implement patient-centered medical homes. Journal of General Internal Medicine 2014 Jul;29 Suppl 2:S547-9.

13. Dobscha SK, Denneson LM, Kovas AE, Corson K, Helmer DA, Bair MJ.  Primary care clinician responses to positive suicidal ideation risk assessments in veterans of Iraq and Afghanistan.  General Hospital Psychiatry. 2014 May-Jun;36(3):310-7.

14. Hirsh AT, Hollingshead NA, Matthias MS, Bair MJ, Kroenke K.  The influence of patient sex, provider sex, and sexist attitudes on pain treatment decisions. Journal of Pain. 2014 May;15(5):551-9.

15. Burgess DJ, Nelson DB, Gravely AA, Bair MJ, Kerns RD, Higgins DM, van Ryn M, Farmer M, Partin MR.  Racial differences in prescription of opioid analgesics for chronic noncancer pain in a national sample of veterans.  Journal of Pain. 2014 Apr;15(4):447-55.

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