Rachel C. Vreeman, MD, MS

Associate Professor of Pediatrics, IU School of Medicine
Co-Director (North America), AMPATH Research Network
Joe and Sarah Ellen Mamlin Scholar of Global Health Research
Director of Research, IU Center for Global Health Research
Faculty Investigator, Center for Health Policy and Professionalism Research, IUSM

   Dr. Vreeman is an Assistant Professor of Pediatrics at the Indiana University School of Medicine, an Affiliated Scientist at the Regenstrief Institute for Health Care, and a member of the Riley Children’s Health Services Research Program.  She is also Director of Research at the Indiana University Center for Global Health, Indiana University School of Medicine and the Joe and Sarah Ellen Mamlin Scholar of Global Health Research, Indiana University School of Medicine.  In addition, she is Co-Director of Pediatric Research for the Academic Model for the Prevention and Treatment of HIV/AIDS (AMPATH), an academic collaboration that provides comprehensive HIV treatment for over 70,000 patients in Kenya.


   Dr. Vreeman’s research addresses two key long-term clinical challenges for children living with HIV: enhanced pediatric adherence to antiretroviral therapy (ART) and disclosure of HIV status in AMPATH pediatric HIV/AIDS clinics in Kenya.  In addition, she has provided guidance to pediatric HIV care issues for AMPATH, including developing and implementing pediatric clinical decision support, improving results reporting for HIV-exposed children, and facilitating monthly adolescent support groups.


   Dr. Vreeman serves as Chair for the Global Pediatric Working Group, International Epidemiologic Databases  for the Evaluation of AIDS, at the National Institutes of Health and on the Adolescent Transition Technical Committee for the International AIDS Society.  She is the recipient of the Watanabe Translational Research Scholar Award from Indiana CTSI.

Dr. Vreeman is board certified in Pediatrics. 


Indiana University Health Profile



  Health Services Research
  Global Health



Physician Groups:  Riley Physicians
 IU Health Physicians
Hospital Privileges:  IU Health Methodist/IU Health University
 Riley Hospital for Children at IU Health



School of Medicine   Michigan State University College of Human Medicine   
Fellowship   Children's Health Services Research
Internship, Residency and Chief Residency   Indiana University School of Medicine  
Master of Science in Clinical Research     Indiana University School of Medicine  

Active Projects

NIH (2016-2020)

“HIV Treatment Failure and Drug Resistance in Western Kenyan Children” (Co-PI)

Evaluation of the prevalence of viral failure and ART resistance among a highly characterized pediatric cohort, in association with detailed adherence data, drug levels, and other factors over time.


NIH/NIMH (2012 – 2017)

“Patient - Centered Disclosure Intervention for HIV - Infected Children” (PI)

Provides funding to assess the effect of a patient-centered intervention guiding disclosure to HIV-infected Kenyan children, using a cluster randomized trial comparing the intervention to routine care. The primary endpoint is probability of disclosure among children, with secondary endpoints of adherence, clinical outcomes, psychological distress and social outcomes.


Selected Publications                                |                            Go To PubMed List >>

1: Tu W, Nyandiko WM, Liu H, Slaven JE, Scanlon ML, Ayaya SO, Vreeman RC. Pharmacokinetics-based adherence measures for antiretroviral therapy in HIV-infected Kenyan children. J Int AIDS Soc. 2017 Jun 7;20(1):1-6. doi: 10.7448/IAS.20.1.21157. PubMed PMID: 28605170; PubMed Central PMCID: PMC5515048.

2: Vreeman RC, McCoy BM, Lee S. Mental health challenges among adolescents living with HIV. J Int AIDS Soc. 2017 May 16;20(Suppl 3):100-109. doi: 10.7448/IAS.20.4.21497. PubMed PMID: 28530045.

3: Sohn AH, Vreeman RC, Judd A. Tracking the transition of adolescents into adult HIV care: a global assessment. J Int AIDS Soc. 2017 May 16;20(Suppl 3):1-3. doi: 10.7448/IAS.20.4.21878. PubMed PMID: 28530035.

4: Haberer JE, Sabin L, Amico KR, Orrell C, Galárraga O, Tsai AC, Vreeman RC, Wilson I, Sam-Agudu NA, Blaschke TF, Vrijens B, Mellins CA, Remien RH, Weiser SD, Lowenthal E, Stirratt MJ, Sow PS, Thomas B, Ford N, Mills E, Lester R, Nachega JB, Bwana BM, Ssewamala F, Mbuagbaw L, Munderi P, Geng E, Bangsberg DR. Improving antiretroviral therapy adherence in resource-limited settings at scale: a discussion of interventions and recommendations. J Int AIDS Soc. 2017 Mar 22;20(1):21371. doi: 10.7448/IAS.20.1/21371. eCollection 2017. PubMed PMID:28630651; PubMed Central PMCID: PMC5467606.

5: McAteer CI, Truong NT, Aluoch J, Deathe AR, Nyandiko WM, Marete I, Vreeman RC. A systematic review of measures of HIV/AIDS stigma in paediatric HIV-infected and HIV-affected populations. J Int AIDS Soc. 2016 Oct 6;19(1):21204. doi: 10.7448/IAS.19.1.21204. eCollection 2016. Review. PubMed PMID: 27717409; PubMedCentral PMCID: PMC5055615.

6: Schlatter AF, Deathe AR, Vreeman RC. The Need for Pediatric Formulations to Treat Children with HIV. AIDS Res Treat. 2016;2016:1654938. doi: 10.1155/2016/1654938. Epub 2016 Jun 16. Review. PubMed PMID: 27413548; PubMed Central PMCID: PMC4927993.

7: Thirumurthy H, Hayashi K, Linnemayr S, Vreeman RC, Levin IP, Bangsberg DR, Brewer NT. Time Preferences Predict Mortality among HIV-Infected Adults Receiving Antiretroviral Therapy in Kenya. PLoS One. 2015 Dec 18;10(12):e0145245. doi: 10.1371/journal.pone.0145245. eCollection 2015. PubMed PMID: 26684298; PubMedCentral PMCID: PMC4684319.

8: Vreeman RC, Scanlon ML, McHenry MS, Nyandiko WM. The physical and psychological effects of HIV infection and its treatment on perinatally HIV-infected children. J Int AIDS Soc. 2015 Dec 2;18(Suppl 6):20258. doi: 10.7448/IAS.18.7.20258. eCollection 2015. PubMed PMID: 26639114; PubMed CentralPMCID: PMC4670835.

9: McHenry MS, Apondi E, Vreeman RC. Vitamin A supplementation for the reduction of the risk of mother-to-child transmission of HIV. Expert Rev Anti Infect Ther. 2015 Jul;13(7):821-4. doi: 10.1586/14787210.2015.1051031. Epub 2015 May 29.PubMed PMID: 26025075.

10: McHenry MS, Dixit A, Vreeman RC. A Systematic Review of Nutritional Supplementation in HIV-Infected Children in Resource-Limited Settings. J Int Assoc Provid AIDS Care. 2015 Jul-Aug;14(4):313-23. doi: 10.1177/2325957414539044. Epub 2014 Jun 18. Review. PubMed PMID: 24943654.

IU CHSOR | 1101 West Tenth Street, 2nd Floor | Campus Address: Regenstrief Building (RF2) | Indianapolis, Indiana 46202-4800 | Ph: 317.274.9026 | Fax: 317.274.9304